Hyaluronidase (Dissolving Fillers)

Dissatisfied with your filler results? There is a solution: Hyaluronidase or Hyalase®. This enzyme can break down the filler, allowing you to quickly get rid of an unwanted result. It is essential to report any allergy to cow proteins or wasp stings before undergoing this treatment.

To ensure you do not have an allergic reaction, Dr. Detollenaere will inject a minimal amount into the skin of your arm. If there is no reaction within 10 minutes, you can proceed with the treatment.

How does Hyalase or Hyaluronidase work?

Hyaluronidase or Hyalase can be injected into the hyaluronic acid filler, partially dissolving it and accelerating its elimination from the body. It can also break down the naturally occurring hyaluronic acid in the body.
When you want to dissolve the filler with Hyalase, it usually has an immediately visible effect, but it may still take up to 2 weeks to see the final result.
Sometimes, repeating the treatment is necessary, especially if the filler was initially treated cautiously to avoid dissolving it completely. It may then be that too little hyaluronidase was injected. However, it’s better to treat twice than to dissolve too much at once — unless you want the filler to be fully removed.

Possibility of allergic reaction

The administration of Hyalase® can lead to anaphylaxis (a severe allergic reaction), which can be life-threatening and requires immediate medical attention.
Symptoms of a severe allergic reaction may include: shortness of breath, wheezing, coughing, difficulty swallowing, swelling of the tongue, eyelids, lips, hoarseness, stomach pain, nausea, or diarrhea.
After the procedure, some other common injection reactions may occur. These reactions include redness, swelling, pain, itching, bruising, and tenderness at the injection site. They are generally described as mild to moderate and usually resolve spontaneously after a few days post-injection. Bruising can sometimes be more significant.

How does a treatment with Hyaluronidase/Hyalase proceed?

Dr. Kim Detollenaere recommends that patients first consider going to the doctor who placed the filler. If they do not wish to do so, Dr. Detollenaere can perform a treatment with Hyalase.

Prijzen Fillers

FAQ

How Many Hyalase Sessions Are Required?

Filler can sometimes be difficult to remove, which may require multiple sessions. This is especially true for the lips and situations where the filler has migrated. If you have had many filler treatments in the past, the filler may have built up and integrated into the tissue. In this case, multiple treatments may be required to completely break down the filler. Smaller filler deposits are likely to dissolve quickly, while larger areas are treated in stages. This may cause the filler to disappear in some areas, while remaining visible in others.

Side effects of Hyalase

The most significant side effect of Hyalase is an allergic reaction, which is rare but variable in severity. Other potential side effects include: injection discomfort, swelling, bruising, infection, cold sores (if the filler dissolves around the mouth), breakdown of natural hyaluronic acid, asymmetry after treatment, and the need for additional treatments depending on the amount, type, and location of filler being dissolved.

When is Hyalase Not Suitable?

Pregnant women will not be treated with Hyalase by doctors.

Waiting Time for New Treatment after Filler Dissolution

It is advisable to wait at least 2 weeks (in some cases a waiting period of 5-6 weeks is advised) before having any further filler treatments. This will allow time for any swelling or bruising to subside and for your lips to recover and produce new collagen. If you have further treatments done too early, the Hyalase solution may attack the new filler, which may lead to unsatisfactory results.